[Neutron] Oak Ridge National Laboratory - Postdoctoral Research Associate in Molecular Biology and Macromolecular Crystallography R&D - NB50340254

[Schwengels, Caty]

Job Posting Title
Postdoctoral Research Associate in Molecular Biology and Macromolecular Crystallography R&D - NB50340254
Posted Date

12/20/2012
End Posting Date
01/11/2013

Purpose
The Neutron Sciences Directorate (NScD) at Oak Ridge National Laboratory operates the High Flux Isotope Reactor (HFIR), the United States' highest flux reactor based neutron source, and the Spallation Neutron Source (SNS), the world's most intense pulsed accelerator based neutron source. Together these facilities operate 24 instruments for neutron scattering research, each year carrying out in excess of 1,000 experiments in the physical, chemical, materials, biological and medical sciences for more than 3,000 visiting scientists. HFIR also provides unique facilities for isotope production and neutron irradiation. To learn more about Neutron Sciences at ORNL go to: http://neutrons.ornl.gov.<http://neutrons.ornl.gov/>

The Biology and Soft Matter Division at Oak Ridge National Laboratory (ORNL) invites applications for a
Biochemist/Molecular Biologist and Macromolecular Crystallographer.

Major Duties/Responsibilities

The successful candidates will carry out research investigating the structure and function of several biological system, including human cAMP dependent protein kinases. This work will involve multi-task, multi-disciplinary efforts involving molecular biology, protein crystallography, small-angle scattering, rational design using computer modeling techniques, and enzymology.

Qualifications Required

* A Ph.D. degree in structural chemistry, biology or a related field is required.
* The candidates should have a proven track record in molecular biology techniques including, plasmid-based heterologous protein expression, protein purification, protein crystallographic data collection, and structure determination and refinement.
* The candidates should be self-motivated, have good interpersonal, communication and presentational skills and demonstrated ability to interact effectively with staff at all levels and to work within a multi-disciplinary team.
* Expertise in isotopic labeling, eukaryotic expression systems, and biofermentation would be a distinct advantage.

Work Directions and Interfaces

Technical questions regarding the position can be directed to Dr. Paul Langan (langanpa at ornl.gov)

Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment. Certain exceptions may be considered. This position is a temporary, full-time assignment for 24 months. This position will remain open for a minimum of 5 days after which it will close when a qualified candidate is identified and/or
hired.


To apply for this position please visit http://jobs.ornl.gov

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